1 Evaluation of the immune response to RTS , S / AS 01 and RTS , S / AS 02 adjuvanted 2 vaccines : randomized , double - blind study in malaria - naïve adults 3
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چکیده
Abbreviations: AE, adverse event; ANOVA, analysis of variance; ATP, according-to9 protocol; CHMP, Committee for Medicinal Products for Human Use; CI, confidence 10 interval; CMI, cell-mediated immune; CS, circumsporozoite; ELISA, enzyme-linked 11 immunosorbent assay; EMA, European Medicines Agency; GMT, geometric mean titer; 12 HBs, hepatitis B surface antigen; HIV, human immunodeficiency virus; ICS, intracellular 13 cytokine staining; IFN, interferon; Ig, immunoglobulin; IL, interleukin; MPL, 14 monophosphoryl lipid A; PBMC, peripheral blood mononuclear cell; SD, standard 15 deviation; TNF, tumor necrosis factor 16
منابع مشابه
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تاریخ انتشار 2014